Structural basis for the disaggregase activity and regulation of Hsp104
The Hsp104 disaggregase is a two-ring ATPase machine that rescues various forms of non-native proteins including the highly resistant amyloid fibers. The structural-mechanistic underpinnings of how the recovery of toxic protein aggregates is promoted and how this potent unfolding activity is prevent...
Збережено в:
| Автори: | , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
eLife Sciences Publications Ltd
2016-11-01
|
| Серія: | eLife |
| Предмети: | |
| Онлайн доступ: | https://elifesciences.org/articles/21516 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|