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Engineering and evolution of molecular chaperones and protein disaggregases with enhanced activity

Cells have evolved a sophisticated proteostasis network to ensure that proteins acquire and retain their native structure and function. Critical components of this network include molecular chaperones and protein disaggregases, which function to prevent and reverse deleterious protein misfolding. Ne...

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Bibliografische Detailangaben
Hauptverfasser: Korrie eMack, James eShorter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016-03-01
Schriftenreihe:Frontiers in Molecular Biosciences
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Online-Zugang:http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00008/full
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