Preclinical profiling of antibody drug conjugates targeting oncofetal chondroitin sulfate
Abstract Antibody-drug conjugates (ADC) offer a targeted cancer treatment approach by delivering cytotoxic payloads directly to tumor cells. However, resistance mechanisms, poor tumor penetration, and off-target toxicity often limit clinical efficacy. Vartumab targets oncofetal chondroitin sulfate (...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2026-01-01
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| coleção: | Cell Death and Disease |
| Acesso em linha: | https://doi.org/10.1038/s41419-026-08420-x |
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