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Oncofetal chondroitin sulfate positive circulating tumor cells as prognostic biomarkers in early-stage melanoma

Abstract Progression occurs in more than 10% of melanoma patients initially diagnosed with local disease, emphasizing the need for improved risk stratification even in early stages. In this study, we used an enrichment method based on recombinant Plasmodium falciparum VAR2CSA protein to enable the c...

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Tallennettuna:
Päätekijät: Judith Sunzenauer, Melanie Rammer, Leonhard Stöckl, Lisa Lugmayr, Viktoria Binder, Eva Strauss, Katharina Priglinger, Victoria Pernsteiner, Helmut Kehrer, Thor Grundtvig Theander, Peter Schröcksnadel, Gerald Webersinke, Ali Salanti, Mette Ørskov Agerbæk, Norbert Sepp
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2026-02-01
Sarja:Scientific Reports
Aiheet:
Melanoma
VAR2CSA
Circulating tumor cells
Cell free DNA
Massively parallel sequencing
Liquid biopsy
Linkit:https://doi.org/10.1038/s41598-026-40072-x
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