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Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway

Flaccidoxide-13-acetate, an active compound isolated from cultured-type soft coral <i>Sinularia gibberosa</i>, has been shown to have inhibitory effects against invasion and cell migration of RT4 and T24 human bladder cancer cells. In our study, we used an 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2...

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Principais autores: Yu-Jen Wu, Tzu-Rong Su, Guo-Fong Dai, Jui-Hsin Su, Chih-I Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-05-01
coleção:Marine Drugs
Assuntos:
flaccidoxide-13-acetate
cultured soft coral <i>Sinularia gibberosa</i>
human bladder cancer
apoptosis
mitochondrial dysfunction
PERK-eIF2<i>α</i>-ATF6-CHOP pathway
p38/JNK
Acesso em linha:https://www.mdpi.com/1660-3397/17/5/287
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