Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway

Flaccidoxide-13-acetate, an active compound isolated from cultured-type soft coral <i>Sinularia gibberosa</i>, has been shown to have inhibitory effects against invasion and cell migration of RT4 and T24 human bladder cancer cells. In our study, we used an 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2...

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Bibliographic Details

Main Authors:	Yu-Jen Wu, Tzu-Rong Su, Guo-Fong Dai, Jui-Hsin Su, Chih-I Liu
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2019-05-01
Series:	Marine Drugs
Subjects:	flaccidoxide-13-acetate cultured soft coral <i>Sinularia gibberosa</i> human bladder cancer apoptosis mitochondrial dysfunction PERK-eIF2<i>α</i>-ATF6-CHOP pathway p38/JNK
Online Access:	https://www.mdpi.com/1660-3397/17/5/287
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