CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction.

Acute kidney injury (AKI) is a common complication during systemic inflammatory response syndrome (SIRS), a potentially deadly clinical condition characterized by whole-body inflammatory state and organ dysfunction. CD44 is a ubiquitously expressed cell-surface transmembrane receptor with multiple f...

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Auteurs principaux:	Elena Rampanelli, Mark C Dessing, Nike Claessen, Gwendoline J D Teske, Sander P J Joosten, Steven T Pals, Jaklien C Leemans, Sandrine Florquin
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2013-01-01
Collection:	PLoS ONE
Accès en ligne:	http://europepmc.org/articles/PMC3871539?pdf=render
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