TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion.

Ischemia reperfusion injury is a common cause of acute kidney injury and is characterized by tubular damage. Mitochondrial DNA is released upon severe tissue injury and can act as a damage-associated molecular pattern via the innate immune receptor TLR9. Here, we investigated the role of TLR9 in the...

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Principais autores:	Pieter J Bakker, Angelique M Scantlebery, Loes M Butter, Nike Claessen, Gwendoline J D Teske, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2015-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC4567139?pdf=render
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