Structural insight into TPX2-stimulated microtubule assembly
During mitosis and meiosis, microtubule (MT) assembly is locally upregulated by the chromatin-dependent Ran-GTP pathway. One of its key targets is the MT-associated spindle assembly factor TPX2. The molecular mechanism of how TPX2 stimulates MT assembly remains unknown because structural information...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications Ltd
2017-11-01
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| Schriftenreihe: | eLife |
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| Online-Zugang: | https://elifesciences.org/articles/30959 |
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