Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens

Exposure to opioids reshapes future reward and motivated behaviors partially by altering the functional output of medium spiny neurons (MSNs) in the nucleus accumbens shell. Here, we investigated how morphine, a highly addictive opioid, alters synaptic transmission and intrinsic excitability on dopa...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dillon S. McDevitt, Benjamin Jonik, Nicholas M. Graziane
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2019-12-01
Цуврал:	Frontiers in Synaptic Neuroscience
Нөхцлүүд:	nucleus accumbens morphine opioid use disorder intrinsic excitability synaptic transmission neuronal activity
Онлайн хандалт:	https://www.frontiersin.org/article/10.3389/fnsyn.2019.00035/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!