Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism

Abstract Background The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse malignant peritoneal mesothelioma (DMPM), a rapidly lethal disease, poorly responsiv...

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Autores principales:	Rihan El Bezawy, Michelandrea De Cesare, Marzia Pennati, Marcello Deraco, Paolo Gandellini, Valentina Zuco, Nadia Zaffaroni
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2017-01-01
Colección:	Journal of Hematology & Oncology
Materias:	miR-34a Diffuse malignant peritoneal mesothelioma Receptor tyrosine kinases AXL c-MET
Acceso en línea:	http://link.springer.com/article/10.1186/s13045-016-0387-6
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