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A low-dose pemetrexed-cisplatin combination regimen induces significant nephrotoxicity in mice

Abstract Background Pemetrexed is combined with cisplatin to treat cancer. Whether pemetrexed-cisplatin combination chemotherapy exacerbates cisplatin nephrotoxicity is unclear. Here, we investigated kidney injury in mice administered a non-lethal low-dose regimen of pemetrexed or cisplatin alone an...

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Principais autores: Samson A. Iwhiwhu, Ravi Kumar, Abdul H. Khan, Jeremiah M. Afolabi, Jada D. Williams, Julia E. de la Cruz, Adebowale Adebiyi
格式: Artigo
語言:Inglês
出版: BMC 2024-10-01
叢編:BMC Nephrology
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在線閱讀:https://doi.org/10.1186/s12882-024-03822-5
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