WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Uda Ho et al find that loss of centriolar scaffold protein WDR62 in mouse testis leads to defects in spermatogenesis. They find that WDR62 deficiency leads to centriole underduplication in spermatocytes and delayed manchette removal in spermatids due to delayed Katanin p80 accumulation.

מידע ביבליוגרפי

Principais autores:	Uda Y. Ho, Chun-Wei Allen Feng, Yvonne Y. Yeap, Amanda L. Bain, Zhe Wei, Belal Shohayeb, Melissa E. Reichelt, Hayden Homer, Kum Kum Khanna, Josephine Bowles, Dominic C. H. Ng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2021-05-01
סדרה:	Communications Biology
גישה מקוונת:	https://doi.org/10.1038/s42003-021-02171-5
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!