Clinical correlates of a negative cerebrospinal fluid α-synuclein seed amplification assay result in Parkinson’s disease

Abstract We investigated the basis and clinical correlates of a negative cerebrospinal fluid (CSF) alpha-synuclein (α-syn) seed amplification assay result in patients with a clinical diagnosis of sporadic or GBA1-associated PD formulated by movement disorder specialists. Out of 473 participants with...

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Hlavní autoři:	Andrea Mastrangelo, Isabel Wurster, Alice Ticca, Stefanie Lerche, Corrado Zenesini, Benjamin Röben, Angela Mammana, Ann-Kathrin Hauser, Edoardo Ruggeri, Christian Deuschle, Erica Vittoriosi, Giuseppe Mario Bentivenga, Claudia Schulte, Sabina Capellari, Kathrin Brockmann, Piero Parchi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-04-01
Edice:	npj Parkinson's Disease
On-line přístup:	https://doi.org/10.1038/s41531-026-01346-3
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