Distinct cerebrospinal fluid proteomic signatures define clinicopathological subtypes of sporadic Creutzfeldt-Jakob disease and predict patient survival

Abstract Sporadic Creutzfeldt-Jakob disease (sCJD) is a highly heterogeneous neurodegenerative disorder encompassing six major histopathological and molecular subtypes, showing diverse clinical features and prognosis. Currently, no accurate biomarkers are available for the antemortem differentiation...

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Үндсэн зохиолчид:	Giuseppe Mario Bentivenga, Angela Mammana, Dea Gogishvili, Simone Baiardi, Erica Vittoriosi, Andrea Mastrangelo, Agustina Ranieri, Isabel M. Houtkamp, Kathrin Brockmann, Sanne Abeln, Sabina Capellari, Piero Parchi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-12-01
Цуврал:	Acta Neuropathologica Communications
Нөхцлүүд:	Prion Creutzfeldt–Jakob disease Biomarker Cerebrospinal fluid Proteomic Proximity extension assay
Онлайн хандалт:	https://doi.org/10.1186/s40478-025-02168-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!