Differences in age-related distribution of CSF alpha-synuclein seeding and Alzheimer profiles between PD with and without GBA1 variants

Abstract We studied the age- and genetic-related prevalence of CSF alpha-Synuclein seeding and Alzheimer profiles in 188 samples from PD participants without GBA1 variants (PDwildtype) and in 129 samples from PD participants with GBA1 variants (PDGBA1). While Alzheimer profiles increased with age in...

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主要な著者:	Stefanie Lerche, Isabel Wurster, Benjamin Roeben, Milan Zimmermann, Marcello Rossi, Angela Mammana, Simone Baiardi, Ann‑Kathrin Hauser, Christian Deuschle, Claudia Schulte, Piero Parchi, Kathrin Brockmann
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-05-01
シリーズ:	npj Parkinson's Disease
オンライン･アクセス:	https://doi.org/10.1038/s41531-025-00978-1
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