Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA
DNA interstrand crosslinks (ICLs) are covalently bound DNA lesions, which are commonly induced by chemotherapeutic drugs, such as cisplatin and mitomycin C or endogenous byproducts of metabolic processes. This type of DNA lesion can block ongoing RNA transcription and DNA replication and thus cause...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021-06-01
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| Serija: | Frontiers in Cell and Developmental Biology |
| Teme: | |
| Online pristup: | https://www.frontiersin.org/articles/10.3389/fcell.2021.699966/full |
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