Mutagenic Potentials of DNA Interstrand Cross-Links Induced by 7,8-Dihydro-8-Oxoadenine
DNA interstrand cross-links (ICLs) are among the most cytotoxic forms of DNA damage, arising when the two strands of the DNA helix are covalently linked by crosslink-inducing agents such as bifunctional alkylating agents and reactive aldehydes. Several studies have demonstrated that ICLs can also be...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2026-01-01
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| Schriftenreihe: | Molecules |
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| Online-Zugang: | https://www.mdpi.com/1420-3049/31/2/291 |
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