Differential role of cytosolic Hsp70s in longevity assurance and protein quality control.
70 kDa heat shock proteins (Hsp70) are essential chaperones of the protein quality control network; vital for cellular fitness and longevity. The four cytosolic Hsp70's in yeast, Ssa1-4, are thought to be functionally redundant but the absence of Ssa1 and Ssa2 causes a severe reduction in cellular r...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science (PLoS)
2021-01-01
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| Schriftenreihe: | PLoS Genetics |
| Online-Zugang: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008951&type=printable |
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