Differential role of cytosolic Hsp70s in longevity assurance and protein quality control.

70 kDa heat shock proteins (Hsp70) are essential chaperones of the protein quality control network; vital for cellular fitness and longevity. The four cytosolic Hsp70's in yeast, Ssa1-4, are thought to be functionally redundant but the absence of Ssa1 and Ssa2 causes a severe reduction in cellular r...

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Bibliografiske detaljer

Principais autores:	Rebecca Andersson, Anna Maria Eisele-Bürger, Sarah Hanzén, Katarina Vielfort, David Öling, Frederik Eisele, Gustav Johansson, Tobias Gustafsson, Kristian Kvint, Thomas Nyström
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2021-01-01
Serier:	PLoS Genetics
Online adgang:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1008951&type=printable
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