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Multistep metabolic engineering of Pichia pastoris for biosynthesis of N‑acetylneuraminic acid

Abstract Free or protein-conjugated N-Acetylneuraminic acid (Neu5Ac) is widely distributed in organisms and possesses diverse biological functions, and for example lactoferrin with Neu5Ac-mediated sialylation exhibits significantly enhanced functional activity compared with non-sialylated lactoferri...

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Bibliografische gegevens
Hoofdauteurs: Xiaomin Zhao, Qian Li, Huiying Luo, Yuan Wang, Xinxin Xu, Wei Zhang, Jie Zhang, Bo Liu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer 2026-02-01
Reeks:Applied Microbiology and Biotechnology
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Online toegang:https://doi.org/10.1007/s00253-026-13744-x
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