Multistep metabolic engineering of Pichia pastoris for biosynthesis of N‑acetylneuraminic acid
Abstract Free or protein-conjugated N-Acetylneuraminic acid (Neu5Ac) is widely distributed in organisms and possesses diverse biological functions, and for example lactoferrin with Neu5Ac-mediated sialylation exhibits significantly enhanced functional activity compared with non-sialylated lactoferri...
Shranjeno v:
| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer
2026-02-01
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| Serija: | Applied Microbiology and Biotechnology |
| Teme: | |
| Online dostop: | https://doi.org/10.1007/s00253-026-13744-x |
| Oznake: |
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