Multistep metabolic engineering of Pichia pastoris for biosynthesis of N‑acetylneuraminic acid
Abstract Free or protein-conjugated N-Acetylneuraminic acid (Neu5Ac) is widely distributed in organisms and possesses diverse biological functions, and for example lactoferrin with Neu5Ac-mediated sialylation exhibits significantly enhanced functional activity compared with non-sialylated lactoferri...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer
2026-02-01
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| Col·lecció: | Applied Microbiology and Biotechnology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1007/s00253-026-13744-x |
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