Liraglutide, a glucagon-like peptide-1 receptor agonist, ameliorates inflammation and apoptosis via inhibition of receptor for advanced glycation end products signaling in AGEs induced chondrocytes

Abstract Background This study aimed to investigate functions of GLP-1R agonist by liraglutide (LIRA) and revealing the mechanism related to AGEs/RAGE in chondrocytes. Methods To illustrate potential effect of GLP-1R agonist on AGEs induced chondrocytes, chondrocytes were administrated by AGEs with...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Xianyu Zhang, Jian Jiang, Jiajia Xu, Jian Chen, Yuntao Gu, Guobao Wu
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2024-07-01
سلاسل:	BMC Musculoskeletal Disorders
الموضوعات:	GLP-1R Liraglutide Osteoarthritis RAGE AGEs
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12891-024-07640-6
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!