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β-Aminoisobutyric acid, L-BAIBA, protects PC12 cells from hydrogen peroxide-induced oxidative stress and apoptosis via activation of the AMPK and PI3K/Akt pathway

β-Aminoisobutyric acid (BAIBA) is a myokine that is secreted from skeletal muscles by the exercise. Recently, increasing evidence has suggested the multifocal physiological activities of BAIBA. In this study, we investigated whether L-BAIBA has protective effects on rat pheochromocytoma (PC12) cells...

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Principais autores: Tomomi Minato, Nobuhisa Nakamura, Tomokazu Saiki, Megumi Miyabe, Mizuho Ito, Tatsuaki Matsubara, Keiko Naruse
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2022-06-01
Series:IBRO Neuroscience Reports
Assuntos:
β-Aminoisobutyric acid (BAIBA)
Neuron
Oxidative stress
Hydrogen peroxide
AMPK
PI3K/Akt
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2667242121000506
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