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Reprogramming of HUVECs into induced pluripotent stem cells (HiPSCs), generation and characterization of HiPSC-derived neurons and astrocytes.

Neurodegenerative diseases are characterized by chronic and progressive structural or functional loss of neurons. Limitations related to the animal models of these human diseases have impeded the development of effective drugs. This emphasizes the need to establish disease models using human-derived...

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主要な著者: Yohannes Haile, Maryam Nakhaei-Nejad, Paul A Boakye, Glen Baker, Peter A Smith, Allan G Murray, Fabrizio Giuliani, Nadia Jahroudi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2015-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC4366250?pdf=render
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