Assessment and Evaluation of Contemporary Approaches for Astrocyte Differentiation from hiPSCs: A Modeling Paradigm for Alzheimer's Disease

Abstract Background Astrocytes have recently gained attention as key players in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease. Numerous differentiation protocols have been developed to study human astrocytes in vitro. However, the properties of the resulting glia are...

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Hlavní autoři:	Veronika Juráková, Balázs Széky, Martina Zapletalová, Anita Fehér, Melinda Zana, Shashank Pandey, Radek Kučera, Omar Šerý, Jiří Hudeček, András Dinnyés, Jan Lochman
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-09-01
Edice:	Biological Procedures Online
Témata:	IPSC Astrocytes FBS Disease modeling Aβ42
On-line přístup:	https://doi.org/10.1186/s12575-024-00257-y
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