Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer
Abstract Background Immunostimulatory therapies targeting immune-suppressive pathways produce durable responses in advanced solid tumors. Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting oxidoreductase that catalyzes the degradation of tryptophan to kynurenine. IDO induces immune tolerance by...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BMJ Publishing Group
2017-10-01
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| Reeks: | Journal for ImmunoTherapy of Cancer |
| Onderwerpen: | |
| Online toegang: | http://link.springer.com/article/10.1186/s40425-017-0285-7 |
| Tags: |
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