Objective measurement and clinical significance of IDO1 protein in hormone receptor-positive breast cancer
Abstract Background Immunostimulatory therapies targeting immune-suppressive pathways produce durable responses in advanced solid tumors. Indoleamine 2,3-dioxygenase (IDO) is the rate-limiting oxidoreductase that catalyzes the degradation of tryptophan to kynurenine. IDO induces immune tolerance by...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Publishing Group
2017-10-01
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| Serie: | Journal for ImmunoTherapy of Cancer |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s40425-017-0285-7 |
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