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Time-sequential fibroblast-to-myofibroblast transition in elastin-variable 3D hydrogel environments by collagen networks

Abstract Background Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with the surrounding extracellular matrix (ECM). However, how this fibroblast-...

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Principais autores: Nhuan T. Do, Sun Young Lee, Yoon Seo Lee, ChaeHo Shin, Daeho Kim, Tae Geol Lee, Jin Gyeong Son, Se-Hwa Kim
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science (AAAS) 2023-10-01
Series:Biomaterials Research
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Acceso en liña:https://doi.org/10.1186/s40824-023-00439-x
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