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Time-sequential fibroblast-to-myofibroblast transition in elastin-variable 3D hydrogel environments by collagen networks

Abstract Background Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with the surrounding extracellular matrix (ECM). However, how this fibroblast-...

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Autori principali: Nhuan T. Do, Sun Young Lee, Yoon Seo Lee, ChaeHo Shin, Daeho Kim, Tae Geol Lee, Jin Gyeong Son, Se-Hwa Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science (AAAS) 2023-10-01
Serie:Biomaterials Research
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Accesso online:https://doi.org/10.1186/s40824-023-00439-x
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