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Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen

Sphingolipids are major components of cellular membranes, and at steady-state level, their metabolic fluxes are tightly controlled. On challenge by external signals, they undergo rapid turnover, which substantially affects the biophysical properties of membrane lipid and protein compartments and, co...

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Autori principali: Elita Avota, Maria Nathalia de Lira, Sibylle Schneider-Schaulies
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-08-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:https://www.frontiersin.org/article/10.3389/fcell.2019.00152/full
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