MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates
Abstract Background Wilms tumor (WT) is the most common renal tumor in childhood. Among others, MYCN copy number gain and MYCN P44L and MAX R60Q mutations have been identified in WT. MYCN encodes a transcription factor that requires dimerization with MAX to activate transcription of numerous target...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2021-10-01
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| coleção: | Cancer Cell International |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12935-021-02259-2 |
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