MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates

Abstract Background Wilms tumor (WT) is the most common renal tumor in childhood. Among others, MYCN copy number gain and MYCN P44L and MAX R60Q mutations have been identified in WT. MYCN encodes a transcription factor that requires dimerization with MAX to activate transcription of numerous target...

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Hlavní autoři:	Ovidio Jiménez Martín, Andreas Schlosser, Rhoikos Furtwängler, Jenny Wegert, Manfred Gessler
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-10-01
Edice:	Cancer Cell International
Témata:	Wilms tumor MYCN MAX Interactome Mutation screening
On-line přístup:	https://doi.org/10.1186/s12935-021-02259-2
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