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MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates

Abstract Background Wilms tumor (WT) is the most common renal tumor in childhood. Among others, MYCN copy number gain and MYCN P44L and MAX R60Q mutations have been identified in WT. MYCN encodes a transcription factor that requires dimerization with MAX to activate transcription of numerous target...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ovidio Jiménez Martín, Andreas Schlosser, Rhoikos Furtwängler, Jenny Wegert, Manfred Gessler
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2021-10-01
Rangatū:Cancer Cell International
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12935-021-02259-2
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