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Chaperone requirements for biosynthesis of the trypanosome variant surface glycoprotein.

Trypanosoma brucei does not respond transcriptionally to several endoplasmic reticulum (ER) stress conditions, including tunicamycin or dithiothreitol, indicating the absence of a conventional unfolded protein response. This suggests divergent mechanisms for quality control (QC) of ER protein foldin...

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Auteurs principaux: Mark C Field, Tatiana Sergeenko, Ya-Nan Wang, Susanne Böhm, Mark Carrington
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2010-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC2797082?pdf=render
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