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Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio.

Externally deposited eggs begin development with an immense cytoplasm and a single overwhelmed nucleus. Rapid mitotic cycles restore normality as the ratio of nuclei to cytoplasm (N/C) increases. A threshold N/C has been widely proposed to activate zygotic genome transcription and onset of morphogen...

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Bibliográfalaš dieđut
Váldodahkkit: Isaac J T Strong, Xiaoyun Lei, Fang Chen, Kai Yuan, Patrick H O'Farrell
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2020-10-01
Ráidu:PLoS Biology
Liŋkkat:https://doi.org/10.1371/journal.pbio.3000891
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