Dominant-negative mutants reveal a role for the Cdk7 kinase at the mid-blastula transition in Drosophila embryos

The metazoan cyclin-dependent kinase Cdk7 was purified originally as part of a biochemical activity called CAK (Cdk-activating kinase) capable of phosphoryla-ting and activating in vitro the Cdks that promote the different cell cycle transitions. Cdk7 is also found in the transcription factor comple...

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Pubblicato in:	EMBO J
Autori principali:	Leclerc, Vincent, Raisin, Sophie, Léopold, Pierre
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2000
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310226/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10747025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.7.1567
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