Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis
Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's loop (TAL). Loss-of-function mutations in the...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2017-05-01
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| Schriftenreihe: | Frontiers in Physiology |
| Schlagworte: | |
| Online-Zugang: | http://journal.frontiersin.org/article/10.3389/fphys.2017.00326/full |
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