Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis

Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's loop (TAL). Loss-of-function mutations in the...

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Autors principals:	Claire Bardet, Sandy Ribes, Yong Wu, Mamadou Tidiane Diallo, Benjamin Salmon, Tilman Breiderhoff, Pascal Houillier, Dominik Müller, Catherine Chaussain
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2017-05-01
Col·lecció:	Frontiers in Physiology
Matèries:	Amelogenesis Imperfecta enamel barrier-forming tight junction protein pore-forming tight junction protein claudins
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fphys.2017.00326/full
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