PTEN-mTORC2 signaling module controls antibody isotype selection and antiviral humoral immunity

IntroductionThe phosphoinositide 3-kinase (PI3K) pathway is a central regulator of activated B cells, yet how PI3K signal strength is interpreted within complex signaling networks to achieve appropriate antibody isotype selection and protective humoral immunity remains incompletely understood. Build...

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Үндсэн зохиолчид:	Bikash Thapa, Yejin Lee, Seongwon Pak, Dongkyu Kim, Hyung-Joo Kwon, Keunwook Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-02-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	antibody isotype selection influenza A virus mTORC2 Notch phosphoinositide 3-kinase pathway PTEN
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1771230/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!