The roles of OGT and its mechanisms in cancer

Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a common and important post-translational modification (PTM) linking O-linked β-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues in proteins. Extensive research indicates its impact on target protein stability, activity,...

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Principais autores:	Xin Liu, Jing Wang, Yaoxian Xiang, Kangjie Wang, Dong Yan, Yingying Tong
格式:	Artigo
语言:	Inglês
出版:	BMC 2024-09-01
丛编:	Cell & Bioscience
主题:	OGT O-GlcNACylation Cancer-promoting factor Drug resistance Immune evasion
在线阅读:	https://doi.org/10.1186/s13578-024-01301-w
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