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Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation

Caveolae are plasma membrane invaginations playing crucial functions, like signal transduction and mechanoprotection. Here, the authors show that caveolae contribute to skin pigmentation by integrating the biochemical and mechanical response of epidermal melanocytes to extracellular cues.

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Bibliografiska uppgifter
Huvudupphov: Lia Domingues, Ilse Hurbain, Floriane Gilles-Marsens, Julia Sirés-Campos, Nathalie André, Melissa Dewulf, Maryse Romao, Christine Viaris de Lesegno, Anne-Sophie Macé, Cédric Blouin, Christelle Guéré, Katell Vié, Graça Raposo, Christophe Lamaze, Cédric Delevoye
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2020-06-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-020-16738-z
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