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Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads

Like most plasma membrane proteins, type I interferon (IFN) receptor (IFNAR) traffics from the outer surface to the inner compartments of the cell. Long considered as a passive means to simply control subunits availability at the plasma membrane, an array of new evidence establishes IFNAR endocytosi...

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Principais autores: Natacha Zanin, Christine Viaris de Lesegno, Christophe Lamaze, Cedric M. Blouin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-01-01
Serier:Frontiers in Immunology
Fag:
transmembrane receptor
interferon
endocytosis
intracellular signaling
traffic
JAK - STAT signaling pathway
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2020.615603/full
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