Retinol from hepatic stellate cells via STRA6 induces lipogenesis on hepatocytes during fibrosis
Abstract Background Hepatic stellate cells (HSCs) are activated in response to liver injury with TIF1γ-suppression, leading to liver fibrosis. Here, we examined the mechanism how reduction of TIF1γ in HSCs induces damage on hepatocytes and liver fibrosis. Method Lrat:Cas9-ERT2:sgTif1γ mice were trea...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BMC
2021-01-01
|
| Cyfres: | Cell & Bioscience |
| Pynciau: | |
| Mynediad Ar-lein: | https://doi.org/10.1186/s13578-020-00509-w |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|