Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.
Chikungunya virus (CHIKV) is an arthritogenic alphavirus that has re-emerged to cause large outbreaks of human infections worldwide. There are currently no approved antivirals for treatment of CHIKV infection. Recently, we reported that the ribonucleoside analog 4'-fluorouridine (4'-FlU) is a highly...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Public Library of Science (PLoS)
2025-01-01
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| মালা: | PLoS Pathogens |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1371/journal.ppat.1012859 |
| ট্যাগগুলো: |
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