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Circulating Follistatin-like 1 associates with inflammation, cognitive decline, and amyloid pathology in Alzheimer’s disease and promotes Aβ-induced neuronal ferroptosis via PI3K/Akt signaling

Abstract Background Alzheimer’s disease (AD) is characterized by progressive cognitive decline, neuroinflammation, and neuronal loss. However, the molecular factors linking amyloid pathology to regulated neuronal death and clinically accessible biomarkers remain incompletely understood. Follistatin-...

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Bibliografiske detaljer
Principais autores: Min Hua, Wen-Ya Chen, Ai-Jin Ma, Man-Yun Cheng, Jie Meng, Lun-Lin Mao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:European Journal of Medical Research
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Online adgang:https://doi.org/10.1186/s40001-026-04341-9
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