Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development

The deltex family protein DTX3 is believed to possess E3 ubiquitin ligase activity, as it contains a classic RING finger domain. However, its biological role and the underlying mechanism in cancer remain largely elusive. Here, we identified DTX3 as a novel mutant p53-interacting protein in ovarian c...

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Principais autores:	Shanshan Wang, Qian Hao, Jiajia Li, Yajie Chen, Hua Lu, Xiaohua Wu, Xiang Zhou
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	KeAi Communications Co., Ltd. 2022-05-01
סדרה:	Genes and Diseases
נושאים:	DTX3 E3 ubiquitin ligase Invasion Mutant p53 Ovarian cancer Proliferation
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2352304220301380
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!