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Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development

The deltex family protein DTX3 is believed to possess E3 ubiquitin ligase activity, as it contains a classic RING finger domain. However, its biological role and the underlying mechanism in cancer remain largely elusive. Here, we identified DTX3 as a novel mutant p53-interacting protein in ovarian c...

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書誌詳細
主要な著者: Shanshan Wang, Qian Hao, Jiajia Li, Yajie Chen, Hua Lu, Xiaohua Wu, Xiang Zhou
フォーマット: Artigo
言語:Inglês
出版事項: KeAi Communications Co., Ltd. 2022-05-01
シリーズ:Genes and Diseases
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2352304220301380
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