ZAR1/2‐Regulated Epigenetic Modifications are Essential for Age‐Associated Oocyte Quality Maintenance and Zygotic Activation

Abstract The developmental competence and epigenetic progression of oocytes gradually become dysregulated with increasing maternal age. However, the mechanisms underlying age‐related epigenetic regulation in oocytes remain poorly understood. Zygote arrest proteins 1 and 2 (ZAR1/2) are two maternal f...

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מידע ביבליוגרפי

Principais autores:	Yan Rong, Yu‐Ke Wu, Yingyan Chen, Qing Liu, Leilei Ai, Yun‐Wen Wu, Yezhang Zhu, Yin‐Li Zhang, Chengkan Liu, Yerong Ma, Xiaomei Tong, Jiamin Jin, Xiaoxuan Li, Yan Zhou, Shu‐Yan Ji, Songying Zhang, Heng‐Yu Fan
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Wiley 2025-02-01
סדרה:	Advanced Science
נושאים:	histone modifications maternal factor oocyte epigenetic maturation oocyte‐to‐embryo transition reproductive aging
גישה מקוונת:	https://doi.org/10.1002/advs.202410305
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